Inflammatory Bowel Disease PRO App This App includes seven NIH PROMIS symptom scales. Each of these seven scales was shown in a large scale study (Kappelman et al 2014) to have differences in patients with IBD vs the general population. Longitudinal analyses showed improved PROMIS scores with improved disease activity and worsening PROMIS scores with worsening disease.
This App can be used as a starting point for launching an App that measures patient reported outcomes in patient with Inflammatory Bowel Disease. It can be customized for your specific patient group and intervention goals. For example, you can include alternate surveys (clinically validated or proprietary), custom reminders, custom care plans, and more.
Background Inflammatory bowel disease includes Crohn’s Disease (CD) and Ulcerative Colitis (UC), and affects over one million Americans. While many therapies exist, effectiveness across populations in the real world has yet to be determined. Recently, the Institute of Medicine selected IBD as a top national priority for comparative effectiveness research.
NIH PROMIS Program The Patient-Reported Outcomes Measurement Information System (PROMIS) scales are a set of validated and publicly available PROs created by the NIH to advance and improve the application of patient reported outcomes in care management as well as research.
Of note, PROMIS surveys are not disease specific, but rather general measures that have been clinically validated, and thus allow comparisons within and between conditions,
Evidence for Use of PROMIS in IBD It was found that IBD patients in a 10,000+ patient cohort had worse PROs as compared with the general population for each of the PROMIS domains tested and included in this App.
The Authors (Kappelman et al 2014) concluded that: "PROMIS item banks appear to be very attractive as outcome measures for clinical and epidemiological research in IBD. They have excellent construct validity, are flexible and efficient, are easy to administer and interpret, and are publicly available. "
How this App can Help CD and UC are diseases that have a significant impact on quality of life. Both CD and UC cannot be medically cured, and are complex multifactorial diseases. By engaging patients with a digital app, care providers can gather data on patient symptoms in a more continuous, non-biased format. This can lead to improved care and reduced costs via earlier detection of non-effectiveness of medicines, as well as earlier detection of complications.
This App can also be used for research purposes in comparing the effectiveness of novel or previously approved therapies.
***PROMIS Surveys are the property of the NIH and US Dept of HHS. License can be obtained from the license owner***
Evaluation of the patient-reported outcomes measurement information system in a large cohort of patients with inflammatory bowel diseases.
Kappelman MD, Long MD, Martin C, DeWalt DA, Kinneer PM, Chen W, Lewis JD, Sandler RS.